Teaching NeuroImage: MRI in multiple system atrophy: "Hot cross bun" sign and hyperintense rim bordering the putamina

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Teaching neuroImage: MRI in multiple system atrophy: "hot cross bun" sign and hyperintense rim bordering the putamina.

A 59-year-old man developed progressive gait ataxia, dysarthria, sexual dysfunction, and Raynaud phenomenon over 2 years. On examination he also manifested bradykinesia and rigidity, postural and action tremor of the upper limbs, and orthostatic hypotension. Family history was negative. Brain MRI disclosed the “hot cross bun” sign typical of multiple system atrophy (MSA) (figure).1,2 This sign ...

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'Hot-cross bun sign' of multiple system atrophy.

OBJECTIVE To investigate whether proton density-weighted imaging can detect the "hot cross bun" sign in the pons in multiple system atrophy with predominant cerebellar ataxia significantly better than T2-weighted imaging at 3T. METHODS Sixteen consecutive patients with multiple system atrophy with predominant cerebellar ataxia according to the Consensus Criteria were reviewed. Axial unenhance...

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"Hot cross bun" sign in two patients with multiple system atrophy-cerebellar.

The “hot cross bun” sign is characterized by cross-shaped T2 signal hyperintensity within the pons and has been said to be specific although not pathognomonic for multiple system atrophy (MSA).1 Case 1 is a 60-year-old woman who presented with progressive spasticity, limb ataxia, and urinary incontinence of 3 1⁄2 years’ duration (figure 1). Case 2 is a 56-year-old man, who had a history of urge...

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Hot cross bun sign in a case with multisystem atrophy

A 65-year-old man came to our clinic with progressive disequilibrium and gait problem since 6 years. During this period, he had also urinary incontinency. On neurologic examination, he had scanning speech and bidirectional nystagmus. There was hypokinesia in upper and lower limbs and on cerebellar tests finger to nose and heel to shin were impaired (severe dysmetria); he was unable to walk with...

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"Hot cross bun" sign resembling multiple system atrophy in a patient with Machado-Joseph disease.

1Department of Neurology, Ataxia Unit, Universidade Federal de São Paulo, São Paulo SP, Brazil; 2Department of Radiology, Universidade Federal de São Paulo and Delboni Auriemo, Diagnósticos da América, São Paulo SP, Brazil. Correspondence: José Luiz Pedroso; Rua Botucatu 740; 04023-900 São Paulo SP Brazil; E-mail: [email protected] Conflict of interest: There is no conflict of interest ...

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ژورنال

عنوان ژورنال: Neurology

سال: 2008

ISSN: 0028-3878,1526-632X

DOI: 10.1212/01.wnl.0000327520.99034.28